58481-14-4
- Product Name：2-cyanoisonicotinic acid ethyl ester
- Molecular Formula：C9H8N2O2
- Purity：99%
- Molecular Weight：176.175
Product Details
pd_meltingpoint:42-44℃
Purity:99%
Offer Chemical Raw Material 2-cyanoisonicotinic acid ethyl ester 58481-14-4 In Stock
- Molecular Formula:C9H8N2O2
- Molecular Weight:176.175
- Vapor Pressure:0.001mmHg at 25°C
- Melting Point:42-44℃
- Refractive Index:1.529
- Boiling Point:308.616 °C at 760 mmHg
- Flash Point:140.446 °C
- PSA：62.98000
- Density:1.21 g/cm3
- LogP:1.12998
Ethyl 2-cyanoisonicotinate(Cas 58481-14-4) Usage
InChI:InChI=1/C9H8N2O2/c1-2-13-9(12)7-3-4-11-8(5-7)6-10/h3-5H,2H2,1H3
58481-14-4 Relevant articles
Synthesis and structural studies of new asymmetric pyridyl-tetrazole ligands for supramolecular chemistry
Sheridan, Ursula,Gallagher, John F.,McGinley, John
, p. 8470 - 8478 (2016)
The synthesis of asymmetric diester deri...
A Bifunctional Reagent Designed for the Mild, Nucleophilic Functionalization of Pyridines
Fier, Patrick S.
supporting information, p. 9499 - 9502 (2017/07/24)
Herein is reported the design and applic...
HOMOLYTIC ALKOXYCARBONYLATION REACTIONS IN TWO-PHASE SYSTEMS 3. INTRODUCTION OF A SINGLE CARBOXYLIC ACID ESTER FUNCTION INTO CYANO- OR ALKOXYCARBONYL SUBSTITUTED N-HETEROAROMATICS
Heinisch, Gottfried,Loetsch, Gerhard
, p. 731 - 744 (2007/10/02)
Homolytic alkoxycarbonylation reactions ...
Site-Selectivity in the Cyanation of 3-Substituted Pyridine 1-Oxides with Trimethylsilanecarbonitrile
Sakamoto, Takao,Kaneda, Soh-ichi,Nishimura, Sumiko,Yamanaka, Hiroshi
, p. 565 - 571 (2007/10/02)
The cyanation of 3-halo-, 3-methoxy-, an...
58481-14-4 Process route
-
-
557-21-1
zinc(II) cyanide
-
-
14906-37-7
ethyl isonicotinate N-oxide
-
-
58481-14-4
2-cyano-isonicotinic acid ethyl ester
| Conditions | Yield |
|---|---|
|
With
N,N-Dimethylcarbamoyl chloride;
In
toluene;
for 2h;
Reflux;
Inert atmosphere;
|
85% |
-
-
773837-37-9
sodium cyanide
-
-
C11H15N2O5S(1+)*CF3O3S(1-)
-
-
58481-14-4
2-cyano-isonicotinic acid ethyl ester
| Conditions | Yield |
|---|---|
|
With
sodium carbonate;
In
N,N-dimethyl-formamide; acetonitrile;
at 20 ℃;
for 1h;
Sealed tube;
|
58481-14-4 Upstream products
-
617-35-6
2-oxo-propionic acid ethyl ester
-
100-70-9
2-Cyanopyridine
-
14906-37-7
ethyl isonicotinate N-oxide
-
7677-24-9
trimethylsilyl cyanide
58481-14-4 Downstream products
-
473924-62-8
Ethyl 2-{[(tert-butoxycarbonyl)amino]methyl}isonicotinate
-
135048-32-7
2-cyanoisonicotinic acid hydrazide
-
468067-23-4
ethyl 2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazol-3-yl)isonicotinate
-
468068-34-0
(3R)-6-cyclohexyl-3-{3-[4-(ethoxycarbonyl)-2-pyridinyl]-1,2,4-oxadiazol-5-yl}hexanoic acid
Relevant Products
-
Methyl ortho hydroxy para aminobenzoateCAS：4136-97-4
-
3-chloro-2-cyano-5-trifluoromethylpyridineCAS：80194-70-3
-
2-cyanoisonicotinic acidCAS：161233-97-2
