52378-64-0
- Product Name：2-Hydroxymethyl-3-bromopyridine
- Molecular Formula：C6H6BrNO
- Purity：99%
- Molecular Weight：188.024
Product Details
Purity:99%
Chinese Manufacturer supply 2-Hydroxymethyl-3-bromopyridine 52378-64-0 in stock with high standard
- Molecular Formula:C6H6BrNO
- Molecular Weight:188.024
- Vapor Pressure:0.006mmHg at 25°C
- Refractive Index:1.599
- Boiling Point:260.929 °C at 760 mmHg
- PKA:12.75±0.10(Predicted)
- Flash Point:111.606 °C
- PSA：33.12000
- Density:1.669 g/cm3
- LogP:1.33640
(3-bromopyridin-2-yl)methanol(Cas 52378-64-0) Usage
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General Description |
(3-bromopyridin-2-yl)methanol is a chemical compound with the molecular formula C6H6BrNO. It is a white to off-white solid that is commonly used in organic synthesis and medicinal chemistry. The presence of a bromine atom and a pyridine ring in its structure makes it a versatile building block for the synthesis of various biologically active compounds and pharmaceuticals. It is also used in the preparation of different heterocyclic compounds and as a reagent in chemical reactions. Additionally, its structure allows for the potential development of new drugs and therapeutic agents for various medical applications. Overall, (3-bromopyridin-2-yl)methanol is an important chemical with potential applications in drug discovery and organic synthesis. |
InChI:InChI=1/C6H6BrNO/c7-5-2-1-3-8-6(5)4-9/h1-3,9H,4H2
52378-64-0 Relevant articles
IMIDAZOPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER
-
, (2018/04/12)
A compound of Formula (IA), or a pharmac...
TRIAZOLOPYRIDINE COMPOUNDS AND USES THEREOF
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Paragraph 00169, (2018/04/11)
A compound of Formula (IA), or a pharmac...
TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF
-
, (2016/07/27)
A compound of Formula (I), or a pharmace...
52378-64-0 Process route
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405174-97-2
3-bromopicolinaldehyde
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52378-64-0
3-bromo-2-hydroxymethyl-pyridine
| Conditions | Yield |
|---|---|
|
With
sodium tetrahydroborate;
In
tetrahydrofuran; methanol;
at 0 - 20 ℃;
for 4h;
|
99% |
|
With
methanol; sodium tetrahydroborate;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 4h;
|
99% |
|
With
methanol; sodium tetrahydroborate;
In
tetrahydrofuran;
at 0 ℃;
for 4h;
|
82% |
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-
38749-79-0
3-bromo-2-picoline
-
-
52378-64-0
3-bromo-2-hydroxymethyl-pyridine
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: selenium(IV) oxide / 1,4-dioxane / 18 h / 120 °C
2: sodium tetrahydroborate / methanol; tetrahydrofuran / 4 h / 0 - 20 °C
With
selenium(IV) oxide; sodium tetrahydroborate;
In
tetrahydrofuran; 1,4-dioxane; methanol;
|
|
|
Multi-step reaction with 2 steps
1: selenium(IV) oxide / 1,4-dioxane / 18 h / 120 °C
2: methanol; sodium tetrahydroborate / tetrahydrofuran / 4 h / 0 - 20 °C
With
methanol; selenium(IV) oxide; sodium tetrahydroborate;
In
tetrahydrofuran; 1,4-dioxane;
|
52378-64-0 Upstream products
-
38749-79-0
3-bromo-2-picoline
-
405174-97-2
3-bromopicolinaldehyde
52378-64-0 Downstream products
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122851-69-8
3-bromo-2-(chloromethyl)pyridine
-
1037830-77-5
3-bromo-2-(2-iodo-phenoxymethyl)-pyridine
-
1037830-85-5
3-bromo-2-(2-iodo-5-methoxy-phenoxymethyl)-pyridine
-
1037830-83-3
3-bromo-2-(5-fluoro-2-iodo-phenoxymethyl)-pyridine
Relevant Products
-
Methyl 6-bromo-3-hydroxy-2-pyridinecarboxylateCAS：321601-48-3
-
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-
3,5-dimethylpyridine-N-oxideCAS：3718-65-8
