What is the 3-Hydroxypicolinic acid?

3-Hydroxypicolinic acid is Light yellow needles, while it's Molecular Formula is C6H5NO3. Light yellow needles 3-Hydroxypicolinic acid (3-HPA) is a matrix material used in matrix-assisted laser desorption/ionization (MALDI) based mass spectroscopy (MS) for the analysis of large biomolecules and quantification of oligonucleotides.

What is the CAS number for 3-Hydroxypicolinic acid?

The CAS number of 3-Hydroxypicolinic acid is 874-24-8.

What is 3-Hydroxypicolinic acid (874-24-8) used for?

3-Hydroxypicolinic acid (3-HPA) is a chemical compound that serves as a matrix material in the field of mass spectroscopy. It is particularly utilized in matrix-assisted laser desorption/ionization (MALDI) based mass spectroscopy (MS) for the analysis of large biomolecules and the quantification of oligonucleotides. Used in Mass Spectrometry Industry: 3-Hydroxypicolinic acid is used as a matrix material for enhancing the ionization process in MALDI-MS, allowing for the effective analysis of large biomolecules. Its properties enable the study of complex biological samples with improved sensitivity and accuracy. 3-Hydroxypicolinic acid is also used as a quantification aid for oligonucleotides, providing a reliable means to measure their concentrations in various applications, such as diagnostics and therapeutics development. This contributes to the advancement of research and the understanding of biological processes at the molecular level.InChI:InChI=1/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)/p-1

What is the 3-Hydroxypicolinic acid?

3-Hydroxypicolinic acid is Light yellow needles, while it's Molecular Formula is C6H5NO3. Light yellow needles 3-Hydroxypicolinic acid (3-HPA) is a matrix material used in matrix-assisted laser desorption/ionization (MALDI) based mass spectroscopy (MS) for the analysis of large biomolecules and quantification of oligonucleotides.

What is the CAS number for 3-Hydroxypicolinic acid?

The CAS number of 3-Hydroxypicolinic acid is 874-24-8.

What is 3-Hydroxypicolinic acid (874-24-8) used for?

3-Hydroxypicolinic acid (3-HPA) is a chemical compound that serves as a matrix material in the field of mass spectroscopy. It is particularly utilized in matrix-assisted laser desorption/ionization (MALDI) based mass spectroscopy (MS) for the analysis of large biomolecules and the quantification of oligonucleotides. Used in Mass Spectrometry Industry: 3-Hydroxypicolinic acid is used as a matrix material for enhancing the ionization process in MALDI-MS, allowing for the effective analysis of large biomolecules. Its properties enable the study of complex biological samples with improved sensitivity and accuracy. 3-Hydroxypicolinic acid is also used as a quantification aid for oligonucleotides, providing a reliable means to measure their concentrations in various applications, such as diagnostics and therapeutics development. This contributes to the advancement of research and the understanding of biological processes at the molecular level.InChI:InChI=1/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)/p-1

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Product classification

874-24-8

Product Name：2-Carboxylic acid-3-hydroxypyridine
Molecular Formula：C₆H₅NO₃
Purity：99%
Molecular Weight：139.111

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Product Details

pd_meltingpoint:208-212 °C

Appearance:Light yellow needles

Purity:99%

Manufacturer Supply Best Quality 2-Carboxylic acid-3-hydroxypyridine 874-24-8 with Efficient Transportation

Molecular Formula:C6H5NO3
Molecular Weight:139.111
Appearance/Colour:Light yellow needles
Vapor Pressure:6.34E-09mmHg at 25°C
Melting Point:208-212 °C
Refractive Index:1.5423 (estimate)
Boiling Point:451.1 °C at 760 mmHg
PKA:1.14±0.50(Predicted)
Flash Point:226.6 °C
PSA：70.42000
Density:1.485 g/cm³
LogP:0.48540

3-Hydroxypicolinic acid(Cas 874-24-8) Usage

Definition

ChEBI: A monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides.

InChI:InChI=1/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)/p-1

874-24-8 Relevant articles

In vitro reconstitution of the biosynthetic pathway of 3-hydroxypicolinic acid

Yun, Xuan,Zhang, Qian,Lv, Meinan,Deng, Hai,Deng, Zixin,Yu, Yi

, p. 454 - 460 (2019)

3-Hydroxypicolinic acid (3-HPA) is an im...

Method for synthesizing 3-hydroxy-2-picolinic acid and derivatives thereof

-

Paragraph 0044-0045, (2020/12/31)

The invention discloses an effective syn...

Kinetics of oxidation of heterocyclic compounds by quinolinium dichromate

Saunte, Hauzachin,Chaubey, Girija S.,Mahanti, Mahendra K.

experimental part, p. 291 - 298 (2012/04/10)

Quinolinium dichromate in sulfuric acid ...

Kinetic studies on the quinolinium dichromate oxidation of heteroacids

Suante,Mahanti

, p. 1813 - 1819 (2007/10/03)

Heterocyclic carboxylic acids reacted wi...

874-24-8 Process route

: 932-35-4
3-hydroxypyridine-2-carbonitrile

: 874-24-8
3-hydroxypyridine-2-carboxylic acid

Conditions

Conditions	Yield
With water; sodium hydroxide; In ethanol; for 12h; Reflux;

: 98140-94-4
3-amino-2-picolinehydroxamic acid

: 874-24-8
3-hydroxypyridine-2-carboxylic acid

: 655244-89-6
3-hydroxy-4-oxo-3,4-dihydro-5-azabenzo-1,2,3-triazine

Conditions

Conditions	Yield
With hydrogenchloride; sodium nitrite; In water; at 5 ℃; for 0.5h;	32% 20%

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