218301-22-5
- Product Name：3-Cyano-4-fluorobenzaldehyde
- Molecular Formula：C8H4FNO
- Purity：99%
- Molecular Weight：149.124
Product Details
pd_meltingpoint:80-84 °C(lit.)
Purity:99%
99% Purity Commercial production 3-Cyano-4-fluorobenzaldehyde 218301-22-5 with Cheapest Price
- Molecular Formula:C8H4FNO
- Molecular Weight:149.124
- Melting Point:80-84 °C(lit.)
- Boiling Point:215.603 °C at 760 mmHg
- Flash Point:84.194 °C
- PSA：40.86000
- Density:1.26 g/cm3
- LogP:1.50988
2-FLUORO-5-FORMYLBENZONITRILE(Cas 218301-22-5) Usage
|
General Description |
2-Fluoro-5-formylbenzonitrile is a benzonitrile derivative. |
InChI:InChI=1S/C8H4FNO/c9-8-2-1-6(5-11)3-7(8)4-10/h1-3,5H
218301-22-5 Relevant articles
Novel indazole derivatives, and use thereof
-
Paragraph 0112-0124, (2019/08/12)
The present invention refers to novel in...
FeCl3·6H2O/acetaldehyde, a versatile system for the deprotection of ketals and acetals via a transacetalization process
Schiavo, Lucie,Jeanmart, Lo?c,Lanners, Steve,Choppin, Sabine,Hanquet, Gilles
, p. 1421 - 1424 (2017/02/23)
Mild and efficient catalytic deprotectio...
HETEROCYCLIC DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF
-
Paragraph 0137; 0138, (2013/09/12)
Disclosed are heterocyclic derivatives, ...
HETEROCYCLIC DERIVATES，PREPARATION PROCESSES AND MEDICAL USES THEREOF
-
Page/Page column 22, (2012/06/16)
Disclosed are heterocyclic derivatives, ...
218301-22-5 Process route
-
-
copper(l) cyanide
-
-
77771-02-9
3-bromo-4-fluorobenzaldehyde
-
-
218301-22-5
2-fluoro-5-formylbenzonitrile
| Conditions | Yield |
|---|---|
|
copper(l) cyanide; 3-bromo-4-fluorobenzaldehyde;
In
1-methyl-pyrrolidin-2-one;
at 170 ℃;
for 24h;
With
celite;
In
1-methyl-pyrrolidin-2-one;
at 80 ℃;
for 1h;
|
100% |
|
In
1-methyl-pyrrolidin-2-one;
at 170 ℃;
for 24h;
|
100% |
|
In
1-methyl-pyrrolidin-2-one;
at 170 ℃;
|
65.4% |
|
In
1-methyl-pyrrolidin-2-one;
at 170 ℃;
for 24h;
|
52% |
|
In
1-methyl-pyrrolidin-2-one;
at 25 - 170 ℃;
|
-
-
920-39-8
isopropylmagnesium bromide
-
-
179897-89-3
5-Bromo-2-fluoro-benzonitrile
-
-
218301-22-5
2-fluoro-5-formylbenzonitrile
| Conditions | Yield |
|---|---|
|
isopropylmagnesium bromide; 5-Bromo-2-fluoro-benzonitrile;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 2h;
Cooling with ice;
N,N-dimethyl-formamide;
In
tetrahydrofuran;
for 3h;
|
218301-22-5 Upstream products
-
544-92-3
copper(I) cyanide
-
77771-02-9
3-bromo-4-fluorobenzaldehyde
-
218301-21-4
2-fluoro-5-bis-bromomethylbenzonitrile
-
180302-35-6
5-bromomethyl-2-fluorobenzonitrile
218301-22-5 Downstream products
-
227609-85-0
2-fluoro-5-(hydroxymethyl)benzonitrile
-
310424-28-3
(Z)-3-(3-Cyano-4-fluoro-phenyl)-acrylic acid methyl ester
-
1379825-89-4
(Z)-2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrle
-
676602-31-6
3-cyano-4-fluorobenzoic acid methyl ester
Relevant Products
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4-cyanopyridine monotrifluoroacetateCAS：29885-70-9
-
3-bromopyridineCAS：626-55-1
-
3-bromo-4-nitropyridineCAS：89364-04-5
