29682-15-3
- Product Name：5-bromopyridine-2-carboxylic acid methyl ester
- Molecular Formula：C7H6BrNO2
- Purity：99%
- Molecular Weight：216.034
Product Details
pd_meltingpoint:101-103 °C
Purity:99%
Manufacturer supply high quality 5-bromopyridine-2-carboxylic acid methyl ester 29682-15-3 with ISO standards
- Molecular Formula:C7H6BrNO2
- Molecular Weight:216.034
- Vapor Pressure:0.00202mmHg at 25°C
- Melting Point:101-103 °C
- Refractive Index:1.553
- Boiling Point:290.9 °C at 760 mmHg
- PKA:-0.67±0.10(Predicted)
- Flash Point:129.7 °C
- PSA：39.19000
- Density:1.579 g/cm3
- LogP:1.63070
5-BROMOPYRIDINE-2-CARBOXYLIC ACID METHYL ESTER(Cas 29682-15-3) Usage
InChI:InChI=1/C7H6BrNO2/c1-11-7(10)6-3-2-5(8)4-9-6/h2-4H,1H3
29682-15-3 Relevant articles
SYNTHETIC RETINOIDS FOR USE IN RAR ACTIVATION
-
Page/Page column 18-19, (2020/09/27)
The present invention relates to compoun...
CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS
-
Paragraph 00559, (2020/07/25)
Compounds, and pharmaceutically acceptab...
HETEROCYCLIC INTEGRIN AGONISTS
-
Paragraph 0246; 0247, (2018/07/29)
The present invention provides polycycli...
A biocatalytic method for the chemoselective aerobic oxidation of aldehydes to carboxylic acids
Knaus, Tanja,Tseliou, Vasilis,Humphreys, Luke D.,Scrutton, Nigel S.,Mutti, Francesco G.
, p. 3931 - 3943 (2018/09/11)
Herein, we present a study on the oxidat...
29682-15-3 Process route
-
-
624-28-2
2,5-dibromopyridine
-
-
67-56-1
methanol
-
-
201230-82-2
carbon monoxide
-
-
29682-15-3
methyl 5-bromopicolinate
| Conditions | Yield |
|---|---|
|
With
1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; triethylamine;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 6h;
under 1551.4 Torr;
|
65% |
|
With
triethylamine;
bis-triphenylphosphine-palladium(II) chloride;
In
acetonitrile;
at 60 ℃;
for 16h;
under 3878.71 Torr;
|
58% |
|
With
triethylamine;
1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate;
In
DMF (N,N-dimethyl-formamide);
at 50 ℃;
for 6h;
under 1551.49 Torr;
Parr apparatus;
|
|
|
With
1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate;
Inert atmosphere;
|
-
-
67-56-1
methanol
-
-
30766-11-1
5-bromoisonicotinic acid
-
-
29682-15-3
methyl 5-bromopicolinate
| Conditions | Yield |
|---|---|
|
With
sulfuric acid;
at 0 - 70 ℃;
for 6h;
|
92% |
|
methanol; 5-bromoisonicotinic acid;
With
thionyl chloride;
at 20 ℃;
for 3h;
Reflux;
With
sodium hydrogencarbonate;
pH=7;
|
86.9% |
|
With
sulfuric acid;
for 117h;
Reflux;
|
86% |
|
With
thionyl chloride;
In
dichloromethane;
at 0 - 50 ℃;
for 12h;
|
80% |
|
With
sulfuric acid;
for 6h;
Reflux;
|
80% |
|
With
sulfuric acid;
at 20 ℃;
for 12h;
Reflux;
|
79% |
|
With
sulfuric acid;
at 60 ℃;
for 18h;
|
76% |
|
With
thionyl chloride;
at 70 ℃;
for 16h;
Inert atmosphere;
Schlenk technique;
|
53% |
|
With
thionyl chloride;
at 65 ℃;
for 2h;
|
|
|
methanol; 5-bromoisonicotinic acid;
sulfuric acid;
at 10 ℃;
Reflux;
With
sodium hydroxide;
In
water;
pH=7 - 8;
|
|
|
With
thionyl chloride;
for 3h;
Reflux;
|
|
|
With
sulfuric acid;
at 0 - 60 ℃;
for 4h;
|
|
|
With
thionyl chloride;
at 0 - 60 ℃;
for 12h;
|
|
|
With
sulfuric acid;
Reflux;
|
10 g |
29682-15-3 Upstream products
-
624-28-2
2,5-dibromopyridine
-
67-56-1
methanol
-
201230-82-2
carbon monoxide
-
223463-13-6
2-iodo-5-bromopyridine
29682-15-3 Downstream products
-
870450-02-5
methyl 5-(4-tert-butyldimethylsilyloxy-but-1-ynyl)picolinate
-
959741-32-3
5-bromo-2-(methoxycarbonyl)-1A[5]-pyridin-1-olate
-
908247-85-8
methyl 5-(3,3-dimethylbut-1-ynyl)picolinate
-
927435-98-1
5-(4-hydroxymethyl-phenyl)-pyridine-2-carboxylic acid methyl ester
Relevant Products
-
Methyl 6-bromo-3-hydroxy-2-pyridinecarboxylateCAS：321601-48-3
-
2-cyanopyridine-N-oxideCAS：2402-98-4
-
2-Amino-5-chloropyridineCAS：1072-98-6
