What is the 2-Amino-5-chloropyridine?

2-Amino-5-chloropyridine is beige to beige-brown crystalline powder, while it's Molecular Formula is C5H5ClN2. beige to beige-brown crystalline powder 5-Chloro-2-pyridinamine is a useful synthetic intermediate. It can be used to synthesize zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists.

What is the CAS number for 2-Amino-5-chloropyridine?

The CAS number of 2-Amino-5-chloropyridine is 1072-98-6.

What is 2-Amino-5-chloropyridine (1072-98-6) used for?

2-Amino-5-chloropyridine, also known as 5-Chloro-2-pyridinamine, is a beige to beige-brown crystalline powder with chemical properties that make it a valuable synthetic intermediate in the pharmaceutical industry. It is characterized by its unique molecular structure, which includes a pyridine ring with an amino group at the 2nd position and a chlorine atom at the 5th position.InChI:InChI=1/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)/p+1

What is the 2-Amino-5-chloropyridine?

2-Amino-5-chloropyridine is beige to beige-brown crystalline powder, while it's Molecular Formula is C5H5ClN2. beige to beige-brown crystalline powder 5-Chloro-2-pyridinamine is a useful synthetic intermediate. It can be used to synthesize zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists.

What is the CAS number for 2-Amino-5-chloropyridine?

The CAS number of 2-Amino-5-chloropyridine is 1072-98-6.

What is 2-Amino-5-chloropyridine (1072-98-6) used for?

2-Amino-5-chloropyridine, also known as 5-Chloro-2-pyridinamine, is a beige to beige-brown crystalline powder with chemical properties that make it a valuable synthetic intermediate in the pharmaceutical industry. It is characterized by its unique molecular structure, which includes a pyridine ring with an amino group at the 2nd position and a chlorine atom at the 5th position.InChI:InChI=1/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)/p+1

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Product classification

1072-98-6

Product Name：2-Amino-5-chloropyridine
Molecular Formula：C₅H₅ClN₂
Purity：99%
Molecular Weight：128.561

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Product Details

pd_meltingpoint:134-138 °C

Appearance:beige to beige-brown crystalline powder

Purity:99%

Buy Good Quality 2-Amino-5-chloropyridine 1072-98-6 with a minimum purity of 99%

Molecular Formula:C5H5ClN2
Molecular Weight:128.561
Appearance/Colour:beige to beige-brown crystalline powder
Vapor Pressure:0.0142mmHg at 25°C
Melting Point:134-138 °C
Refractive Index:1.5110 (estimate)
Boiling Point:257.8 °C at 760 mmHg
PKA:4.67±0.13(Predicted)
Flash Point:94.7 °C
PSA：38.91000
Density:1.326 g/cm³
LogP:1.89840

2-Amino-5-chloropyridine(Cas 1072-98-6) Usage

Synthesis Reference(s)	The Journal of Organic Chemistry, 41, p. 93, 1976 DOI: 10.1021/jo00863a020
Purification Methods	Recrystallise this base from pet ether. It sublimes at 50o/0.5mm. [Beilstein 22 II 332, 22/8 V 541.]

InChI:InChI=1/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)/p+1

1072-98-6 Relevant articles

Electroorganic synthesis of 6-aminonicotinic acid from 2-amino-5-chloropyridine

Ramesh Raju,Krishna Mohan,Jayarama Reddy

, p. 4133 - 4135 (2003)

A synthesis of 6-aminonicotinic acid by ...

Convenient chlorination of some special aromatic compounds using N-chlorosuccinimide

Gan, Zongjie,Hu, Bin,Song, Qiao,Xu, Yungen

, p. 1074 - 1078 (2012)

Some chlorinated aromatic compounds, inc...

Activator free, expeditious and eco-friendly chlorination of activated arenes by N-chloro-N-(phenylsulfonyl)benzene sulfonamide (NCBSI)

Misal, Balu,Palav, Amey,Ganwir, Prerna,Chaturbhuj, Ganesh

, (2021)

N-Chloro-N-(phenylsulfonyl)benzene sulfo...

N-azinylpyridinium N-aminides: An approach to pyrazolopyridines via an intramolecular radical pathway

Nu?ez, Araceli,García de Viedma, Aránzazu,Martínez-Barrasa, Valentín,Burgos, Carolina,Alvarez-Builla, Julio

, p. 1093 - 1096 (2002)

Intramolecular radical arylation, under ...

Method for catalytic synthesis of 2-amino-5-chloropyridine by microwave synergistic lewis acidic ionic liquid

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Paragraph 0018-0020, (2020/10/14)

The invention relates to a method for ca...

One-step high-efficient high-selective synthesis of 2 - amino -5 - chloro pyridine method (by machine translation)

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Paragraph 0023; 0024; 0025; 0026; 0027; 0028, (2019/01/23)

The invention belongs to the technical f...

BF3·SMe2 for Thiomethylation, Nitro Reduction and Tandem Reduction/SMe Insertion of Nitrogen Heterocycles

S?derstr?m, Marcus,Zamaratski, Edouard,Odell, Luke R.

, p. 5402 - 5408 (2019/06/27)

Herein, a general, solvent-free and stra...

1072-98-6 Process route

: 504-29-0
2-aminopyridine

: 1072-98-6
5-chloro-2-pyridylamine

: 4214-74-8
3,5-dichloropyridin-2-amine

Conditions

Conditions	Yield
With chloroform; chlorine;
With chlorine; acetic acid;
With chloroform; chlorine; acetic acid;
With ethanol; chlorine;
With ethanol; chlorine;
With chloroform; chlorine; acetic acid;
With chloroform; chlorine;
With chlorine; acetic acid;