13602-12-5
- Product Name：Isonicotinic acid-N-oxide
- Molecular Formula：C6H5 N O3
- Purity：99%
- Molecular Weight：139.111
Product Details
pd_meltingpoint:270-271 ºC
Appearance:Slightly beige.
Purity:99%
Buy Quality Isonicotinic acid-N-oxide 13602-12-5 In Stock with Immediately Delivery
- Molecular Formula:C6H5 N O3
- Molecular Weight:139.111
- Appearance/Colour:Slightly beige.
- Vapor Pressure:1.34E-09mmHg at 25°C
- Melting Point:270-271 ºC
- Refractive Index:1.5423 (estimate)
- Boiling Point:469°Cat760mmHg
- PKA:3.66±0.10(Predicted)
- Flash Point:237.4°C
- PSA：62.76000
- Density:1.34g/cm3
- LogP:0.81330
Pyridine-4-carboxylic acid N-oxide(Cas 13602-12-5) Usage
|
General Description |
Isonicotinic acid N-oxide interacts with 3d metal(II) perchlorates in ethanol-triethyl orthoformate leading to partial substitution of perchlorate with isonicotinate-N-oxide anionic groups. It reacts with AgClO4 or AgBF4 to yield distinct crystalline products. It forms polymeric lanthanide(III) complexes. |
InChI:InChI=1/C6H5NO3/c8-6(9)5-1-3-7(10)4-2-5/h1-4H,(H,8,9)/p-1
13602-12-5 Relevant articles
Design, synthesis, and biological evaluation of 17-cyclopropylmethyl-3, 14β-dihydroxy-4,5α-epoxy-6β-[(4′-pyridyl)carboxamido] morphinan derivatives as peripheral selective μ opioid receptor agents
Yuan, Yunyun,Elbegdorj, Orgil,Chen, Jianyang,Akubathini, Shashidhar K.,Zhang, Feng,Stevens, David L.,Beletskaya, Irina O.,Scoggins, Krista L.,Zhang, Zhenxian,Gerk, Phillip M.,Selley, Dana E.,Akbarali, Hamid I.,Dewey, William L.,Zhang, Yan
, p. 10118 - 10129 (2012)
Peripheral selective μ opioid receptor (...
Synthesis of pyridinecarboxylic acid N-oxides and their amides under microwave irradiation conditions
Khrustalev
, p. 162 - 163 (2009)
-
Ligand-regulated assemblies of three 1D to 3D Cu(II) coordination polymers: Structural diversities and magnetic properties
Cuo, Lei-Lei,Kang, Yi-Fan,Ma, Yang-Min,Wang, Yun-Luo,Xu, Li,Zhang, Wen-Qian
, (2020)
Three structurally diverse Cu(II) coordi...
-
Emerson,Rees
, p. 1923 (1962)
-
Design of 3-D europium(iii)-organic frameworks based on pyridine carboxylate N-oxide and acyclic binary carboxylate: Syntheses, structures, and luminescence properties
Zhang, Lijuan,Xu, Donghua,Zhou, Yunshan,Jiang, Fei
, p. 2470 - 2478 (2010)
Four europium(iii) complexes of 3-D open...
Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure-Activity Relationship, Inhibition Mechanism, Metabolism, and in Vivo Studies
Jung, Sascha,Fuchs, Natalie,Johe, Patrick,Wagner, Annika,Diehl, Erika,Yuliani, Tri,Zimmer, Collin,Barthels, Fabian,Zimmermann, Robert A.,Klein, Philipp,Waigel, Waldemar,Meyr, Jessica,Opatz, Till,Tenzer, Stefan,Distler, Ute,R?der, Hans-Joachim,Kersten, Christian,Engels, Bernd,Hellmich, Ute A.,Klein, Jochen,Schirmeister, Tanja
, p. 12322 - 12358 (2021/09/02)
Rhodesain is a major cysteine protease o...
Preparation method of topiroxostat
-
Paragraph 0047-0051, (2021/07/28)
The invention provides a preparation met...
Solvent- and halide-free synthesis of pyridine-2-yl substituted ureas through facile C-H functionalization of pyridine: N -oxides
Rassadin, Valentin A.,Zimin, Dmitry P.,Raskil'dina, Gulnara Z.,Ivanov, Alexander Yu.,Boyarskiy, Vadim P.,Zlotskii, Semen S.,Kukushkin, Vadim Yu.
supporting information, p. 6630 - 6636 (2018/03/01)
A novel solvent- and halide-free atom-ec...
13602-12-5 Process route
-
-
108-89-4
picoline
-
-
1003-67-4
4-methylpyridine-1-oxide
-
-
55-22-1
pyridine-4-carboxylic acid
-
-
13602-12-5
Isonicotinic acid N-oxide
| Conditions | Yield |
|---|---|
|
With
acetylperoxyborate;
MnAlPO-5;
In
water;
at 95 - 115 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
acetylperoxyborate;
TS-1 (titanium silicalite);
In
water;
at 65 - 95 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
tert.-butylhydroperoxide;
MnAlPO-5;
In
water;
at 95 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
peracetic acid; sodium hydroxide; sodium acetate; acetic acid;
MnAlPO-5;
In
water;
at 95 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
peracetic acid; sodium hydroxide; sodium tetraborate; acetic acid;
MnAlPO-5;
In
water;
at 95 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
peracetic acid; acetic acid;
MnAlPO-5;
In
water;
at 95 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
dihydrogen peroxide;
MnAlPO-5;
In
water;
at 95 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
sodium hydroxide; peroxyacetic acid; sodium tetraborate pentahydrate;
In
water; acetic acid;
at 94.84 ℃;
for 4h;
|
89.5 mol % 4.2 mol % 1.5 mol % |
|
With
acetyl peroxyborate;
In
water;
at 94.84 ℃;
for 4h;
|
40.5 mol % 35.8 mol % 16.0 mol % |
|
With
peroxyacetic acid; sodium acetate;
In
water;
at 94.84 ℃;
for 4h;
|
45.3 mol % 33.7 mol % 15.5 mol % |
-
-
108-99-6
3-Methylpyridine
-
-
1003-67-4
4-methylpyridine-1-oxide
-
-
13602-12-5
Isonicotinic acid N-oxide
| Conditions | Yield |
|---|---|
|
With
acetyl peroxyborate;
In
water;
at 94.84 ℃;
for 4h;
|
50.0 mol % 41.5 mol % |
13602-12-5 Upstream products
-
1003-67-4
4-methylpyridine-1-oxide
-
55-22-1
pyridine-4-carboxylic acid
-
83813-60-9
6-Hydroxy-2'-pyridin-4-yl-bicyclohexyl-6,1'-diene-2,3'-dione
-
108-89-4
picoline
13602-12-5 Downstream products
-
55-22-1
pyridine-4-carboxylic acid
-
6313-54-8
2-chloroisonicotinic acid,
-
498-94-2
isonipecotic acid
-
3783-38-8
methyl isonicotinate N-oxide
Relevant Products
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Methyl ortho hydroxy para aminobenzoateCAS：4136-97-4
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Methyl 6-bromo-3-hydroxy-2-pyridinecarboxylateCAS：321601-48-3
-
3-chloro-2-cyanopyridineCAS：38180-46-0
