38180-46-0
- Product Name：3-chloro-2-cyanopyridine
- Molecular Formula：C6H3ClN2
- Purity：99%
- Molecular Weight：138.556
Product Details
pd_meltingpoint:81-83 °C
Appearance:Light Yellow Solid
Purity:99%
Manufacturer Sells Best Quality 3-chloro-2-cyanopyridine 38180-46-0 with stock
- Molecular Formula:C6H3ClN2
- Molecular Weight:138.556
- Appearance/Colour:Light Yellow Solid
- Vapor Pressure:0.0121mmHg at 25°C
- Melting Point:81-83 °C
- Refractive Index:1.565
- Boiling Point:260.7 °C at 760 mmHg
- PKA:-2.60±0.10(Predicted)
- Flash Point:111.4 °C
- PSA：36.68000
- Density:1.33 g/cm3
- LogP:1.60668
2-Cyano-3-chloropyridine(Cas 38180-46-0) Usage
InChI:InChI=1/C6H3ClN2/c7-5-2-1-3-9-6(5)4-8/h1-3H
38180-46-0 Relevant articles
C?H Cyanation of 6-Ring N-Containing Heteroaromatics
Elbert, Bryony L.,Farley, Alistair J. M.,Gorman, Timothy W.,Johnson, Tarn C.,Genicot, Christophe,Lallemand, Bénédicte,Pasau, Patrick,Flasz, Jakub,Castro, José L.,MacCoss, Malcolm,Paton, Robert S.,Schofield, Christopher J.,Smith, Martin D.,Willis, Michael C.,Dixon, Darren J.
supporting information, p. 14733 - 14737 (2017/10/07)
Heteroaromatic nitriles are important co...
Site-Selectivity in the Cyanation of 3-Substituted Pyridine 1-Oxides with Trimethylsilanecarbonitrile
Sakamoto, Takao,Kaneda, Soh-ichi,Nishimura, Sumiko,Yamanaka, Hiroshi
, p. 565 - 571 (2007/10/02)
The cyanation of 3-halo-, 3-methoxy-, an...
REGIOSELECTIVE CYANATION OF 3-SUBSTITUTED PYRIDINE 1-OXIDES
Fife, Wilmer K.
, p. 93 - 96 (2007/10/02)
Cyanation of 3-X-pyridine 1-oxides with ...
Reactions of Halogenomethanes in the Vapour Phase. Part 5. The Reactions of Imidazolines, Anils, and 1-Methylimidazole with Chloroform at 550 deg C, and a Comparison with their Liquid-Phase Reactions with Trichloroacetate Ion or Hexachloroacetone and Base
Busby, Reginald E.,Khan, Mohammad A.,Khan, Mohammad R.,Parrick, John,Shaw, C. J. Granville
, p. 1431 - 1435 (2007/10/02)
The vapor-phase reactions of imidazoline...
38180-46-0 Process route
-
-
1851-22-5
3-chloropyridine-N-oxide
-
-
7677-24-9
trimethylsilyl cyanide
-
-
89809-64-3
2-cyano-5-chloropyridine
-
-
38180-46-0
3-chloro-2-cyanopyridine
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
acetonitrile;
for 6h;
Heating;
|
85% 6% |
|
With
N,N-Dimethylcarbamoyl chloride;
In
dichloromethane;
Yield given. Yields of byproduct given;
Ambient temperature;
|
-
-
626-60-8
3-Chloropyridine
-
-
7677-24-9
trimethylsilyl cyanide
-
-
89809-64-3
2-cyano-5-chloropyridine
-
-
38180-46-0
3-chloro-2-cyanopyridine
-
-
68325-15-5
3-chloro-isonicotinonitrile
| Conditions | Yield |
|---|---|
|
3-Chloropyridine;
With
trifluoromethylsulfonic anhydride;
In
chloroform;
at 20 ℃;
for 1h;
Inert atmosphere;
Sealed tube;
trimethylsilyl cyanide;
In
chloroform;
at 60 ℃;
for 3h;
Inert atmosphere;
Sealed tube;
With
4-methyl-morpholine;
In
chloroform;
at 60 ℃;
for 17h;
Overall yield = 63 %;
Inert atmosphere;
Sealed tube;
|
38180-46-0 Upstream products
-
616-47-7
1-methyl-1H-imidazole
-
67-66-3
chloroform
-
4513-94-4
1H-pyrrole-2-carbonitrile
-
1851-22-5
3-chloropyridine-N-oxide
38180-46-0 Downstream products
-
131109-75-6
1-(3-chloropyridin-2-yl)ethanone
-
111042-90-1
methyl 3-amino-thieno[3,2-b]pyridine-2-carboxylate
-
114080-95-4
3-chloronicotinamide
-
53636-60-5
3-(4-methoxy-benzylsulfanyl)-pyridine-2-carbonitrile
Relevant Products
-
(S)-3-Aminobutyronitrile hydrochlorideCAS：1073666-54-2
-
Isonicotinic acid-N-oxideCAS：13602-12-5
-
N-Oxidized ethyl isonicotinateCAS：14906-37-7
